What is the difference between Chrome and IE in SharePoint environment?

For almost every environment, I have seen deployments always have a challenge or two.

The current challenge I am running into is that the form worked on IE before now doesn't anymore but it works on Chrome.
This got figured out. It was InputFormTextBox in RichTextMode with required attribute. For IE, it couldn't validate the field because CauseValidation wasn't set.

When testing browsers compatibility, one should set both Browser and Document Mode in the same browser version.